CV

• Name: Mohammad Bagher Majnooni
• DD: 1985 Iran
• E-mail: mb.majnooni64@yahoo.com, mb.majnooni64@gmail.com
• Education:
•   Professional Doctorate of Pharmacy (Pharm.D.), School of Pharmacy, Kermanshah University of Medical Sciences, Iran, 2010.
• Ph.D. of Pharmacognosy, School of Pharmacy, Kermanshah University of Medical Sciences, Iran, 2018-2023.
• Employment:
• Researcher, Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran, 2010- 2013.
• Responsible personnel of Albourz Distributing Company, 2013-2014
• Head of quality control, Bakhtar Biochemi Pharmaceutical Company, 2014-2016
• Ph.D. student of pharmacognosy, School of Pharmacy, Kermanshah University of Medical Sciences, Iran, 2018-2023.

·         R&D and QC consultant of Bakhtar Biochemi pharmaceutical company, 2022-present

·         Faculty Member of the Pharmaceutical Sciences Research Center, Health Institute, Faculty of Pharmacy, Kermanshah University of Medical Sciences, Iran. 2024-present

·          http://orcid.org/0000-0001-5053-333X

·         https://scholar.google.com/citations?user=5aFwguYAAAAJ&hl=en

·         https://isid.research.ac.ir/Mohammadbagher_Majnoni

·         https://www.scopus.com/authid/detail.uri?authorId=24279804300

·         https://research.kums.ac.ir/webdocument/load.action?webdocument_code=8000&masterCode=3000664

·         Telephone: office: 08334276471, mobile: 0989183563818

·         AWARDS:

1-      1^st best Student Researcher, Kermanshah University of Medical Sciences, 2008

2-      1^st best Pharm.D student in School of Pharmacy, Kermanshah University of Medical Sciences, 2009

3-      1^st best Student Researcher, Kermanshah University of Medical Sciences,2010

4-      3 ^rd best selected team in Razi Festival, 2011

5-      1 ^st best Student Researcher, Kermanshah University of Medical Sciences, 2012

6-      1^st best poster presentation in Pharmacy Updates Congress, 2019

7-      Selected for the Top Student Talent Award of the National Elites Foundation, 2020

8-      1^st Best pharmacognosy Ph.D. Student in the School of Pharmacy, Kermanshah University of Medical Sciences (Grade point average 17.76), 2020

9-      1^st best Ph.D. Student Researcher, Kermanshah University of Medical Sciences,2021

10-  The top student researcher of the Health and Medical Education ministry, 2021

11-  1st best Ph.D. Student Researcher, Kermanshah University of Medical Sciences,2022

Skills:

Formulation & Development:

o   Expert in Formulation of synthetic pharmaceuticals, Natural Products, Dietary Supplements, and Cosmeceuticals.

o   Product Development & Scale-up from Laboratory to Industrial Scale.

o   Knowledge of ICH Guidelines, Pharmacopoeial Standards (USP, EP), and Regulatory Requirements.

Regulatory & Quality Systems:

o   Good Manufacturing Practice (GMP) & Good Laboratory Practice (GLP)

o   Quality Control (QC) & Quality Assurance (QA)

o   Method Validation & Stability Studies

Technical Proficiency:

o   Analytical Instrumentation (Column Chromatography, HPLC, GC, LC-MS/MS, TLC, NMR, UV-Vis)

o   Pharmaceutical Technology & Process Optimization

o   Phytochemistry Studies

Publication: 48 paper

1. Majnooni MB, Naseri M, Bakhshy-Chenary S, Zeinalii Y, Azadi M, Farzaei MH, Fakhri S, Ghanadian M, Echeverría J. Modulation of the PI3K/Akt signaling pathway by steroidal saponins: Therapeutic implications in cancer. Frontiers in Pharmacology.2026;17:1779073.

2. Majnooni MB, Ghanadian M, Mansouri K, Bahrami GR, Mojarrab M. Unveiling the Bioactive Potential of Allium colchicifolium Boiss Bulb Flavonoids: Anti-cancer Activities, and Computational Exploration of Anti-angiogenic Mechanisms. Iranian Journal of Pharmaceutical Research: IJPR. 2025;24(1):e163152.

3. Hesari, M., Shackebaei, D., Mohammadi, P., Majnooni MB., Fatemeh Yarmohammadi.Diosmin-Hesperidin Combination Improves Post-Ischemic Cardiac Recovery Via AKT/mTORC1 Modulation in Doxorubicin-Treated Rats. Cell Biochem Biophys (2026). https://doi.org/10.1007/s12013-026-02000-8

4. Fakhri S, Gravandi MM, Majnooni MB, Farzaei MH, Abbaszadeh F, Rashidi K, Echeverria J. Ferula ammoniacum gum aqueous extract employs anti-inflammatory and antioxidant mechanisms to combat aluminum chloride-induced Alzheimer's disease in rats: Possible involvement of opioid pathways. Frontiers in Pharmacology.2026; 16:1708643.

5. Etebari M, Salehi M, Majnooni M B, Ghanadian M. Genotoxic Effects of Dracocephalum Lindbergii Essential Oil Assessed by Comet Assay: Dose-Dependent Increase in DNA Damage Markers.J Rep Pharm Sci.2025;13(1):e165509.

6. Lotfaliani M, Ayatollahi SA, Kobarfard F, Majnooni MB, Mirzaei A, Ghanadian M, et al. Flavonoids Isolated From Delphinium semibarbatum Flowering Aerial Parts With Their Antibacterial, Antibiofilm, and Antiswarming Activity Against Proteus mirabilis and Staphylococcus aureus. Journal of Food Biochemistry. 2024;2024(1):9994944.

7. Iranpanah A, Majnooni MB, Biganeh H, Amirian R, Rastegari‐Pouyani M, Filosa R, et al. Exploiting new strategies in combating head and neck carcinoma: A comprehensive review on phytochemical approaches passing through PI3K/Akt/mTOR signaling pathway. Phytotherapy Research. 2024;38(7):3736-62.

8. Iranpanah A, Fakhri S, Bahrami G, Majnooni MB, Gravandi MM, Taghavi S, et al. Protective effect of a hydromethanolic extract from Fraxinus excelsior L. bark against a rat model of aluminum chloride-induced Alzheimer's disease: Relevance to its anti-inflammatory and antioxidant effects. Journal of Ethnopharmacology. 2024;323:117708.

9. Majnooni MB, Ghanadian SM, Mojarrab M, Bahrami G, Mansouri K, Mirzaei A, et al. Antibacterial, antibiofilm, antiswarming, and antioxidant activities of flavonoids isolated from Allium colchicifolium leaves. Journal of Food Biochemistry. 2023;2023(1):5521661.

10. Majnooni MB, Fakhri S, Ghanadian SM, Bahrami G, Mansouri K, Iranpanah A, et al. Inhibiting angiogenesis by anti-cancer saponins: from phytochemistry to cellular signaling pathways. Metabolites. 2023;13(3):323.

11. Majnooni MB, Mohammadi S, Bahrami G, Mohammadi-Noori E, Farzaei MH. Chemical Composition, Total Phenolic Content, and Anti-Ulcerative Colitis Effects of Extract and Essential Oil of Cupressus arizonica Greene Fruits. Traditional and Integrative Medicine. 2022.

12. Kazemi F, Mojarrab M, Bahrami G, Miraghaei SS, Hadidi S, Majnooni MB. The Alkaloids of Isatis indigotica as Promising Candidates against COVID-19: A Molecular Docking Simulation for Drug Development. Journal of Reports in Pharmaceutical Sciences. 2022;11(2):165-81.

13. Fakhri S, Jafarian S, Majnooni MB, Farzaei MH, Mohammadi-Noori E, Khan H. Anti-nociceptive and anti-inflammatory activities of the essential oil isolated from Cupressus arizonica Greene fruits. The Korean journal of pain. 2022;35(1):33-42.

14. Zobeiri M, Parvizi F, Kalhori MR, Majnooni MB, Farzaei MH, Abdollahi M. Targeting miRNA by natural products: a novel therapeutic approach for nonalcoholic fatty liver. Evidence‐based Complementary and Alternative Medicine. 2021;2021(1):6641031.

15. Majnooni MB, Miraghaee S-S, Keshavarzi S, Mohammadi B, Sajadimajd S, Hatami R, et al. Rapid and sensitive UHPLC-DAD method for simultaneous determination of sofosbuvir and ledipasvir in human serum. Journal of pharmaceutical and biomedical analysis. 2021;195:113860.

16. Majnooni MB, Fakhri S, Bahrami G, Naseri M, Farzaei MH, Echeverría J. Alkaloids as potential phytochemicals against SARS‐CoV‐2: Approaches to the associated pivotal mechanisms. Evidence‐Based Complementary and Alternative Medicine. 2021;2021(1):6632623.

17. Majnooni MB, Ataee M, Bahrami G, Heydarpour F, Aneva IY, Farzaei MH, et al. The effects of co‐administration of artichoke leaf extract supplementation with metformin and vitamin E in patients with nonalcoholic fatty liver disease: A randomized clinical trial. Phytotherapy Research. 2021;35(11):6324-34.

18. Fakhri S, Piri S, Majnooni MB, Farzaei MH, Echeverria J. Targeting neurological manifestations of coronaviruses by candidate phytochemicals: a mechanistic approach. Frontiers in Pharmacology. 2021;11:621099.

19. Fakhri S, Patra JK, Das SK, Das G, Majnooni MB, Farzaei MH. Ginger and heart health: from mechanisms to therapeutics. Current molecular pharmacology. 2021;14(6):943-59.

20. Fakhri S, Iranpanah A, Gravandi MM, Moradi SZ, Ranjbari M, Majnooni MB, et al. Natural products attenuate PI3K/Akt/mTOR signaling pathway: A promising strategy in regulating neurodegeneration. Phytomedicine. 2021;91:153664.

21. Ahmadi-Jouybari T, Aghaei A, Ataee M, Navabi J, Anvari B, Jouybari HA, et al. Synergistic effect of cumin (Cuminum cyminum L.) decoction alongside with three-drug and four-drug treatment protocols on helicobacter pylori eradication. Journal of Reports in Pharmaceutical Sciences. 2021;10(1):66-70.

22. Majnooni MB, Fakhri S, Shokoohinia Y, Mojarrab M, Kazemi-Afrakoti S, Farzaei MH. Isofraxidin: Synthesis, Biosynthesis, Isolation, Pharmacokinetic and Pharmacological Properties. Molecules. 2020;25:2040.

23. Majnooni MB, Fakhri S, Shokoohinia Y, Kiyani N, Stage K, Mohammadi P, et al. Phytochemicals: potential therapeutic interventions against coronavirus-associated lung injury. Frontiers in Pharmacology. 2020;11:588467.

24. Majnooni MB, Fakhri S, Smeriglio A, Trombetta D, Croley CR, Bhattacharyya P, et al. Antiangiogenic effects of coumarins against cancer: From chemistry to medicine. Molecules. 2019;24(23):4278.

25. Majnooni MB, Mohammadi B, Jalili R, Babaei A, Bahrami G. Determination of fatty acids by high-performance liquid chromatography and fluorescence detection using precolumn derivatization with 9-fluorenylmethyl chloroformate. Journal of Liquid Chromatography & Related Technologies. 2016;39(19-20):877-81.

26. Shahlaei M, Bahrami G, Abdolmaleki S, Sadrjavadi K, Majnooni MB. Application of unfolded principal component analysis–radial basis function neural network for determination of celecoxib in human serum by three-dimensional excitation–emission matrix fluorescence spectroscopy. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2015;138:675-83.

27. Sadrjavadi K, Shahlaei M, Bahrami G, Majnooni MB, Mohebbi M. Comparison of correlation ranking and eigenvalue ranking unfolded principal component regression for direct determination of naproxen in human serum using excitation–emission matrix fluorescence spectroscopy. Journal of the Iranian Chemical Society. 2015;12(6):967-77.

28. Majnooni MB, Jalili R, Mohammadi B, Miraghaee SS, Fakhri S, Bahrami G. Development and validation of a new method for determination of topiramate in bulk and pharmaceutical formulation using high performance liquid chromatography-UV detection after pre-column derivatization. Journal of Reports in Pharmaceutical Sciences. 2014;3(2):179-83.

29. Arkan E, Shamsipur M, Saber R, Karimi Z, Majnooni M. A novel electrochemical sensor based on a silver nanoparticle modified carbon ionic liquid electrode for selective and sensitive determination of levetiracetam in pharmaceutical tablets and blood plasma samples. Analytical Methods. 2014;6(7):2197-204.

30. Majnooni M, Mohammadi-Farani A, Gholivand M, Nikbakht M, Bahrami G. Chemical composition and anxiolytic evaluation of Achillea wilhelmsii C. Koch essential oil in rat. Research in Pharmaceutical Sciences. 2013;8(4):269.

31. hesari m, shackebaei d, asadmobini a, majnooni mb. protective effect of paracetamole on doxorubicin induced cardiotoxicity in isolated rat heart. 2013.

32. Ahmadi-Jouibari T, Nikbakht MR, Mansouri K, Majnooni MB. Cytotoxic effects of the essential oil from Achillea wilhelmsii C. Koch. Journal of Reports in Pharmaceutical Sciences. 2013;2(2):98-102.

33. Adibi H, Majnooni MB, Mostafaie A, Mansouri K, Mohammadi M. Synthesis, and in-vitro cytotoxicity studies of a series of triazene derivatives on human cancer cell lines. Iranian Journal of Pharmaceutical Research: IJPR. 2013;12(4):695.

34. Abolghazi M, Abiri R, Majnooni MB, Fallahi B, Babanejad M. Antibacterial effect of six plant extracts on some pathogenic‎ bacteria. Journal of Clinical Research in Paramedical Sciences. 2013;2(3).

35. Mohammadi B, Majnooni MB, Khatabi PM, Jalili R, Bahrami G. 9-Fluorenylmethyl chloroformate as a fluorescence-labeling reagent for derivatization of carboxylic acid moiety of sodium valproate using liquid chromatography/tandem mass spectrometry for binding characterization: A human pharmacokinetic study. Journal of Chromatography B. 2012;880:12-8.

36. Mohammadi B, Majnooni MB, Afnanzade N-s, Jalili R, Bahrami G. Simple and rapid ultra high performance liquid chromatographic (UHPLC) method for the determination of levetiracetam in human serum: application to a bioequivalence study. African Journal of Pharmacy and Pharmacology. 2012;6(27):2017-22.

37. Majnooni MB, Mansouri K, Gholivand M-B, Mostafaie A, Mohammadi-Motlagh H-R, Afnanzade N-S, et al. Chemical composition, cytotoxicity and antioxidant activities of the essential oil from the leaves of Citrus aurantium L. African journal of biotechnology. 2012;11(2):498-503.

38. Majnooni MB, Gholivand MB, Khodadadian M, Afnanzade N-s, Bahrami G. Electroreduction of tacrolimus as immunosuppressant agent at hanging mercury drop electrode: application to determination in pharmaceutical formulation. Journal of Reports in Pharmaceutical Sciences. 2012;1(1):41-8.

39. Majnooni M, Mohammadi B, Jalili R, Bahrami G. Rapid and sensitive high performance liquid chromatographic determination of zonisamide in human serum application to a pharmacokinetic study. Indian Journal of Pharmaceutical Sciences. 2012;74(4):36

40. Majnooni M, Abiri R, Afnanzade N, Malek Khatabi P. Study of antibacterial effects of hydro-alcoholic extract of 8 medicinal herbs against vancomycin resistant staphylococcus aureus. Journal of Medicinal Plants. 2012;11(41):103-10.

41. Adibi H, Abiri R, Mallakpour S, Zolfigol MA, Majnooni MB. Evaluation of in vitro antimicrobial and antioxidant activities of 4-substituted-1, 2, 4-triazolidine-3, 5-dione derivatives. Journal of Reports in Pharmaceutical Sciences. 2012;1(2):87-93.

42. Adibi H, Rashidi A, Khodaei MM, Alizadeh A, Majnooni MB, Pakravan N, et al. Catecholthioether derivatives: preliminary study of in-vitro antimicrobial and antioxidant activities. Chemical and Pharmaceutical Bulletin. 2011;59(9):1149-52.

43. Shackebaei D, Godini A, Abolghazi M, Majnooni MB, Hesari M. Protection of ischemic and reperfused rat heart by aqueous extract of Urtica dioica. International Cardiovascular Research Journal. 2010;4(3).

44. Gholivand MB, Khodadadian M, Majnooni MB, Bahrami G. Electroreduction of zonisamide at hanging mercury drop electrode and its determination in pharmaceutical formulations and spiked human serum samples. Analytical letters. 2010;43(2):269-79.

45. Bahrami G, Mohammadi B, Khatabi PM, Farzaei MH, Majnooni MB, Bahoosh SR. Application of one-step liquid chromatography–electrospray tandem MS/MS and collision-induced dissociation to quantification of ezetimibe and identification of its glucuronated metabolite in human serum: A pharmacokinetic study. Journal of Chromatography B. 2010;878(28):2789-95.

46. Adibi H, Massah AR, Majnooni MB, Shahidi S, Afshar M, Abiri R, et al. Synthesis, characterization, and antimicrobial evaluation of sulfonamides containing n-acyl moieties catalyzed by bismuth (III) salts under both solvent and solvent-free conditions. Synthetic Communications®. 2010;40(18):2753-66.

47. Abiri R, Majnooni M, Malek Khattabi P, Adibi H. Study of antimicrobial effects of Trigonella Foenum hydro-alcoholic extract on different bacterial strains. Medical Laboratory Journal. 2009;3(1):0-.

48. Massah AR, Adibi H, Khodarahmi R, Abiri R, Majnooni MB, Shahidi S, et al. Synthesis, in vitro antibacterial and carbonic anhydrase II inhibitory activities of N-acylsulfonamides using silica sulfuric acid as an efficient catalyst under both solvent-free and heterogeneous conditions. Bioorganic & medicinal chemistry. 2008;16(10):5465-72.

Projects:

Implementation and collaboration of more than 40 research projects:

https://research.kums.ac.ir/webdocument/load.action?webdocument_code=8000&masterCode=3000664

Interests:

1. Research & Professional Interests

·         Herbal Product Formulation & Standardization: Expertise in the research, development, and quality control of herbal medicinal products, dietary supplements, and cosmeceuticals. Focused on ensuring safety, efficacy, and reproducibility through advanced standardization protocols.

·         Phytochemistry & Natural Products Research: Dedicated to the isolation, identification, and analytical profiling of bioactive compounds from medicinal plants for drug discovery and product development.

·         Pharmaceutical Quality Systems & GMP Compliance: Extensive experience in pharmaceutical manufacturing quality control, GMP auditing, and ensuring regulatory compliance for chemical, herbal, and supplementary products.

2. Professional Experience

·         GMP Inspector / Quality Assurance Specialist: Conducted audits and inspections of pharmaceutical production facilities to ensure strict adherence to Good Manufacturing Practice (GMP) guidelines, covering areas from raw material control to finished product release.

3. Teaching & Research

·         Pharmaceutical Sciences Educator: Experience in lecturing and mentoring in areas of phytochemistry, pharmacognosy, drug formulation, and quality control.

Research & Development: Leading research projects in phytopharmaceutical development, from plant extraction and standardization to analytical method validation